NexGard Spectra®—Parasite control made simple


This article is sponsored content brought to you by Boehringer Ingelheim.

Summer brings with it increased parasite pressure. Traditionally, broad-spectrum control of the important endo- and ectoparasites of dogs has required the use of multiple products, potentially with different dosing intervals and methods of administration. This can be confusing for pet owners, and may reduce compliance.  

NexGard Spectra simplifies parasite control in dogs by combining two highly effective active ingredients in a palatable beef-flavoured chew. Containing afoxolaner, a potent insecticide and acaricide, and milbemycin oxime, a broad-spectrum nematocide, NexGard Spectra was initially registered in 2017 to provide broad-spectrum protection against fleas, ticks (including paralysis ticks), heartworm, and gastrointestinal nematodes (roundworms, hookworms and whipworm). 

Further controlled clinical studies have demonstrated the effectiveness of afoxolaner in NexGard Spectra against mites, resulting in the addition of indications for the treatment and control of demodectic mange (caused by Demodex spp.), sarcoptic mange (caused by Sarcoptes scabiei), and otodectic mange (caused by Otodectes cynotis).1-3

The NexGard Spectra label indications for the control of gastrointestinal worms have also been expanded to include two further species. NexGard Spectra has a label indication for the prevention of flea tapeworm (Dipylidium caninum) infestations. Control of this parasite is achieved through the action of afoxolaner on the primary intermediate host, the flea. Afoxolaner, due to its rapid speed of kill for fleas, prevents maturation of the immature stage, and prevents flea tapeworm infestation in dogs.4,5

NexGard Spectra has been demonstrated to control an additional species of hookworm, Ancylostoma ceylanicum. As a zoonotic risk, A. ceylanicum is unique among the hookworms in that it not only has the potential for causing cutaneous larva migrans, but may also develop into adult worms in the intestine of humans, resulting in a patent infection. Due to their short pre-patent period (as little as two weeks), regular anthelmintic treatment of at-risk animals is recommended to provide optimal protection against hookworms.6,7

NexGard Spectra is the optimal parasite control solution for clients looking for simplicity, providing the most complete protection against fleas, ticks, mites, heartworm and intestinal worms, in a tasty monthly chew.

A full listing of current label indications for NexGard Spectra can be found below. See product label for full details and directions for use. 

NexGard Spectra Label Indications 

For the treatment and prevention of flea infestations, control of ticks and mites, prevention of heartworm, and treatment and control of intestinal worms in dogs and puppies from eight weeks of age.

  • NexGard Spectra rapidly kills adult fleas and is indicated for the treatment and prevention of flea (Ctenocephalides spp.) infestations, for the control of newly acquired adult fleas and for the control of flea allergy dermatitis. Following administration, fleas are killed within 6-8 hours. Fleas can transmit flea tapeworm (Dipylidium caninum). Effective flea control with NexGard Spectra prevents flea tapeworm infestation in dogs.
  • NexGard Spectra treats and controls paralysis ticks (Ixodes holocyclus), brown dog ticks (Rhipicephalus sanguineus) and bush ticks (Haemaphysalis longicornis) for one month. It provides effective control of pre-existing paralysis tick infestations within 24 hours. Ixodes holocyclus ticks do not occur in WA. In tick season, daily searching for, and removal of, any ticks found is recommended.
  • NexGard Spectra treats and controls demodectic mange caused by Demodex spp., sarcoptic mange caused by Sarcoptes scabiei and ear mite infestations.
  • NexGard Spectra prevents heartworm disease caused by Dirofilaria immitis and treats and controls roundworms (Toxocara canis and Toxascaris leonina), hookworms (Ancylostoma caninum and A. ceylanicum) and whipworms (Trichuris vulpis).

For more info, speak with your Boehringer Ingelheim Territory Manager, call our Customer Care Team on 1800 808 691, or email Or visit Boehringer Ingelheim.

parasite control


1.Beugnet, F., et al (2016) Efficacy of afoxolaner in a clinical field study in dogs naturally infested with Sarcoptes scabiei. Parasite, 23, 26.

2.Carithers, D., et al (2016) Assessment of afoxolaner efficacy against Otodectes cynotis infestations of dogs. Parasit Vectors, 9(1), 635.

3.Lebon, W., et al (2018) Efficacy of two formulations of afoxolaner (NexGard® and NexGard Spectra®) for the treatment of generalised demodicosis in dogs, in veterinary dermatology referral centers in Europe. Parasit Vectors, 11(1), 506.

4.Beugnet, F., et al (2017) Preventive efficacy of NexGard Spectra® against Dipylidium caninum infection in dogs using a natural flea infestation model. Parasite, 24, 16.

5.Beugnet, F., et al (2015) Comparative speed of efficacy against Ctenocephalides felis of two oral treatments for dogs containing either afoxolaner or fluralaner. Vet Parasitol, 207(3-4), 297-301.

6.Tielemans, E., et al (2017) Efficacy of afoxolaner plus milbemycin oxime chewable tablets (NexGard Spectra®, Merial) against adult Ancylostoma ceylanicum hookworm, in dogs. Vet Parasitol, 238, 87-89.

7.Tropical Council for Companion Animal Parasites (2018) Guidelines for the diagnosis, treatment and control of canine endoparasites in the tropics. 1st Edition, PET-0054-2019. 


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